Hepatoid carcinoma of the ovary without staining for alpha-fetoprotein
نویسندگان
چکیده
Primary hepatoid carcinoma of the ovary (HCO) is a rare type of ovarian tumor that resembles hepatocellular carcinoma both histologically and immunohistochemically in its staining for alpha-fetoprotein (AFP). We describe a 51-year-old woman who presented to our hospital complaining of abdominal pain. Computed tomography scan revealed a large tumor in the pelvis. She underwent total hysterectomy and bilateral salpingo-oophorectomy with tumorectomy. A right ovarian mass measuring 9×8×6 cm was found. Histological diagnosis was hepatoid carcinoma of the right ovary. But, immunohistochemically, tumor cells were not immunoreactive for AFP and there was no elevation of serum AFP level. This is the first report of an ovarian carcinoma with typical histologic features of HCO with negative staining for AFP and normal level of serum AFP in the world.
منابع مشابه
Metastatic hepatoid carcinoma of ovarian origin - a case report from northern Pakistan
•Hepatoid carcinoma of the ovary is rapidly progressing rare epithelial ovarian tumor.•The term 'hepatoid' refers to the morphological resemblance with hepatocellular carcinoma.•Final diagnosis is made via positive staining for alpha fetoprotein along with immunohistochemistry•Combination chemotherapy can be considered superior over the targeted agents while treating this tumor.
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